Carrier Genetic Testing
How Does Next Generation Gene Sequencing Work?
NGS: next generation massive sequencing is a powerful new technology that can examine the entire genetic code of a female donor, and predict how her DNA, or genetic code, will interact with the genetic information of the male partner before conception.
Until recently donors have been tested for the most common single gene disorders in the population, but there are hundreds of additional uncommon genetic disorders. It is estimated that each of us carries several potentially serious recessive genes, but they are rarely present in both the male and the female. However, many extremely serious and even fatal diseases are caused by these rare mutations. It is currently possible to test more than 600 genetic conditions for 4,000 mutations that are known to cause diseases that have no cure.
Egg donors from The World Egg Bank are young healthy women with no reported personal or family history of genetic disease. Currently, the standard practice is to test donors for the American College of Obstetrics and Gynecology’s (ACOG) recommended panel of common recessive genes. Additional NGS testing can determine which Donors test positive for any of these additional 4,000 mutations. If there is a positive genetic mutation in the same sequence for the male and the egg donor, then a new egg donor is selected to avoid the possibility of disease.
- Exclusively Available Through The World Egg Bank
- 8% of couples have “shared” genetic mutations that can lead to disease in their offspring
- 20% of infant mortality in developed countries is caused by genetic disorders
- Every person has an average of 2.3 recessive mutations that can cause genetic diseases
How Our Advance NGS is Unique:
The World Egg Bank is the only Egg Bank to offer this unique state-of-the-art NGS testing. This phenomenal tool is the only one of its kind as there is no analysis done by statistical computations (probabilities based on general population statistics) but is entirely based on individual DNA testing. It is accurate, and is an analysis of the DNA for only the specific egg donor and sperm member involved in the conception of your child. Secondly, results derived from this technology have been validated.
Want more information? Visit http://cgt.igenomix.com/
Testing is sourced through Igenomix, and the test is called CGT/Carrier Genetic Testing™. The company offering this test, Igenomix, has avoided risky matches for 227 couples using donor egg. If you do not choose to use CGT, The World Egg Bank donor you choose will be tested with our ACOG approved genetic testing panel.